Jack Doyle is an investigator who is focused on indigenous criminal activity. Okwaho'kó:wa is a First Nations advocate who is active in protecting indigenous rights. This 'abrasive American' and 'troublesome Indian' join together to locate a missing person — a 15-year-old runaway Cree girl from a reserve in Northern Ontario. To succeed, the duo must overcome mutual hostility and distrust. Weighed down by racial prejudices, they embark on a journey through the dark side of society. Will society's ills encumber them? Or will the challenge embolden them to cooperate?