Lee Know

Mitochondria and the Future of Medicine

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With information for patients and practitioners on optimizing mitochondrial function for greater health and longevity

Why do we age? Why does cancer develop? What's the connection between heart failure and Alzheimer's disease, or infertility and hearing loss? Can we extend lifespan, and if so, how? What is the Exercise Paradox? Why do antioxidant supplements sometimes do more harm than good? Many will be amazed to learn that all these questions, and many more, can be answered by a single point of discussion: mitochondria and bioenergetics.

In Mitochondria and the Future of Medicine, Naturopathic Doctor Lee Know tells the epic story of mitochondria, the widely misunderstood and often-overlooked powerhouses of our cells. The legendary saga began over two billion years ago, when one bacterium entered another without being digested, which would evolve to create the first mitochondrion. Since then, for life to exist beyond single-celled bacteria, it's the mitochondria that have been responsible for this life-giving energy. By understanding how our mitochondria work, in fact, it is possible to add years to our lives, and life to our years.

Current research, however, has revealed a dark side: many seemingly disconnected degenerative diseases have tangled roots in dysfunctional mitochondria. However, modern research has also endowed us with the knowledge on how to optimize its function, which is of critical importance to our health and longevity. Lee Know offers cutting-edge information on supplementation and lifestyle changes for mitochondrial optimization, such as CoQ10, D-Ribose, cannabinoids, and ketogenic dietary therapy, and how to implement their use successfully. Mitochondria and the Future of Medicine is an invaluable resource for practitioners interested in mitochondrial medicine and the true roots of chronic illness and disease, as well as anyone interested in optimizing their health.
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385 printed pages
Original publication
2018
Publication year
2018
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Quotes

  • Soliloquios Literarioshas quoted4 years ago
    Despite the fact that we can produce it, CoQ10 becomes more vitamin-­like as we age because we produce less and less with advancing age (with the body slowing its production starting in our late twenties or early thirties). Many believe this is by design, because by our late twenties, our prime reproductive years are behind us, and as we raise our children to take our spot on this finite planet, reduction of CoQ10 is Nature’s way of preparing us for our eventual exit. Considering how important mitochondria and oxidative phosphorylation are to our health and longevity, by reducing the production of this one molecule, the body can start winding things down to make room and free up resources for the next generation
  • Soliloquios Literarioshas quoted4 years ago
    Coenzyme Q10 (CoQ10) is an antioxidant, a membrane stabilizer, and a vital component in the mitochondrial ETC. It also regulates gene expression and apoptosis; is an essential cofactor of uncoupling proteins and permeability transition pores; and has anti-­inflammatory, redox modulatory, and neuroprotective effects.

    CoQ10 is a vitamin-like molecule that is naturally present in just about every single cell in our body. Like vitamins, it is absolutely essential to life. However, since our bodies produce CoQ10, it’s not technically a vitamin. In order to produce CoQ10, the cell needs an amino acid called tyrosine, at least eight different vitamins, and several trace minerals. A deficiency of any of these impairs the cells’ ability to produce CoQ10
  • Soliloquios Literarioshas quoted4 years ago
    Dark Chocolate

    Table 3.2 shows the high content of PQQ in cocoa powder. Perhaps this is one reason for the many health benefits associated with chocolate consumption. Of course, there are plenty of other health-giving compounds in chocolate (such as flavonols, theobromine, and epicatechin), but we should definitely not discount the high concentration of PQQ

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