Venice, 1468. Sosia Simeon is a lover of many men in the fabled city, though married to one she despises. On the edge of the Grand Canal, Wendelin von Speyer sets up the first printing press in Venice and looks for the book that will make his fortune. When he publishes Catullus, the poet whose unrequited love inspired the most tender and erotic poems of antiquity, a scandal is set in motion that will change all their lives forever.