In the context of the safe management of disused sealed radioactive sources, an important and emerging issue of immediate concern is the management of depleted uranium (DU) contained in radiation shielding materials, as potential radioactive waste. This publication presents relevant information on technical issues and factors, as well as specific Member State experiences leading to the identification of potential options for the management of DU shields. Various options for safe, secure and cost-effective solutions have been explored, ranging from returning to manufacturer, including reuse, recycling, storage and disposal in licensed facilities.