The Langford College Art Museum Director Margaret Anderson is murdered mysteriously in her bed, a red feather replacing her vivisected heart. Pearl, Margaret's closest friend and a psychic, experiences confusing images related to the murder. Offering to help the police, Pearl connects with the local Orlando TV news anchorman Nick Rondinaro. Nick gets her access to additional murder sites as the bizarre murders continue.
In her house in the spiritualist community of Argo, Pearl paints the images on canvas. Driven by dreams, she goes with Nick to Chichen Itza in Mexico to make sense of her dream images. They meet Mexican Professor Guillermo Vasquez who explains the astronomy and mythology of the Mayan's 2012 End Time predictions and sorcerers from the Cult of Kukulkan — The Feathered Serpent.
Pearl sees images of Michelangelo's “Last Judgment”, Picasso's “Guernica”, and VanGogh's “Starry Nights” connected to Mayan sacrifices and the murders. She worries about the world's future, that Christian, Muslim and Jewish prophecies fueling religious conflicts may align with the Mayan predictions to destroy the world!