Peter Attia

As we’ll see in chapter 11, endurance exercise produces factors that directly target regions of the brain responsible for cognition and memory.

grip strength, an excellent proxy for overall strength, was strongly and inversely associated with the incidence of dementia

the greater someone’s grip strength, the lower their risk of dementia.

I now tell patients that exercise is, full stop and hands down, the best tool we have in the neurodegeneration prevention tool kit.

Sleep is also a very powerful tool against Alzheimer’s disease, as we’ll see in chapter 16. Sleep is when our brain heals itself; while we are in deep sleep our brains are essentially “cleaning house,”

Another somewhat surprising risk factor that has emerged is hearing loss. Studies have found that hearing loss is clearly associated with Alzheimer’s disease, but it’s not a direct symptom.

Another surprising intervention that may help reduce systemic inflammation, and possibly Alzheimer’s disease risk, is brushing and flossing one’s teeth.

(Remember, cognition is one of the three key vectors of healthspan.)

Absorb what is useful, discard what is useless, and add what is specifically your own.
—Bruce Lee

The first is exercise, which I consider to be by far the most potent domain in terms of its impact on both lifespan and healthspan. Of course, exercise is not just one thing, so I break it down into its components of aerobic efficiency, maximum aerobic output (VO2 max), strength, and stability,